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Modafinil for the treatment of excessive daytime sleepiness in Parkinson's disease: a case report

Rabinstein A, Shulman LM, Weiner WJ.

Department of Neurology,
University of Miami School of Medicine,
1501 NW 9 Avenue, 33136, Miami, FL, USA
2001 Oct;7(4):287-288

ABSTRACT

We report a 59 year old woman with levodopa responsive Parkinson's disease who developed excessive daytime sleepiness [Epworth Sleepiness Scale (ESS) score of 13].  Treatment with Modafinil 400mg daily within two weeks produced a subjective improvement in her daytime sleepiness (ESS score after treatment is 8) with no significant change in her PD motor symptomotology.

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